Emerge Webinar Series Episode 3
Wednesday July 28 at 17:00 CEST
Controls for Quantitative Proteomics (AKA How to Mass Spec Responsibly)
Julia Robbins, Genome Sciences Department, University of Washington, Seattle
Webinar: A Next Generation Solution to Quality and Efficient Sample Prep for Single-Cell Multiomics Precision Oncology
Tuesday July 27 2021, 5 am – 6 am (CEST)
Single-cell sequencing and multiomics analysis can be powerful tools across the therapy development pipeline, from discovery to diagnostics. The weak signal-to-noise inherent to these methods demands stringent and careful sample preparation, particularly when those samples come from cancer patients.
We are pleased to host Jonathan Scolnick, Ph.D., Founder and Chief Science Officer at Proteona, a precision oncology company based in Singapore. Proteona uses insights from single-cell multiomics measurements to improve cancer patient care. Joining Dr. Scolnick is Chyan Ying Ke, Ph.D., Associate Director of Bioapplications at Curiox. Dr. Ke leads the Curiox R&D team in Singapore.
Webinar attendees will learn:
– How Proteona approaches single-cell multiomics
– Insights gleaned from single-cell analysis for precision oncology
– Specific workflow challenges associated with single-cell multiomics
– How Curiox Laminar Wash™ technology addresses single-cell ‘omics sample prep
– How Curiox enables single-cell multiomics data collection at Proteona
The timing of the live event is tailored for our Asia-Pacific audience. Regardless of your time zone, we encourage all interested attendees to register, leave a question or comment in the field below, and watch the webinar on-demand shortly after its conclusion.
Webinar: Clinical Data Interpretation Service in NGS Workflows
Celemics & Strand Life Sciences Bioinfomratics Solution Service
Celemics provides robust clinical interpretation services through Strand pipeline that combines bioinformatics algorithms, public data from external sources/knowledge databases, visualization interfaces and reporting capabilities, enabling the user to analyze the NGS data and generate clinical report from Celemics panels, for individual samples.
Emerge Webinar Series Episode 2
Wednesday June 30 at 17:00 CEST
High-throughput spatial-temporal proteomics for the study of phospho-signaling dynamics
Dr. Ana Martinez del Val
Novo Nordisk Foundation Center for Protein Research, Denmark
The presentation will focus on the application of high-throughput spatial-temporal proteomics workflows for the study of phospho-signaling dynamics.
Dynamic changes in subcellular localization of signaling proteins is a general concept that eukaryotic cells evolved for eliciting a coordinated response to stimuli. Mass spectrometry-based proteomics in combination with subcellular fractionation can provide comprehensive maps of spatio-temporal regulation of cells, but involves laborious methods that did not include phospho-proteome analysis.
Ana will present a high-throughput workflow, based on sequential cell fractionation, to profile the global proteome and phospho-proteome dynamics across six distinct subcellular fractions. The workflow was benchmarked by studying spatio-temporal EGFR phospho-signaling dynamics in-vitro (HeLa cell cultures) and in-vivo in mouse tissues, and was also employed to assess the spatio-temporal events in response to stress related signaling, such as hyperosmotic shock, revealing cellular relocation of ribosomal proteins.
Ana obtained her PhD at the Proteomics Unit in the Spanish National Cancer Research Center, where she was working on quantitative proteomics and phosphoproteomics applied to stem cell biology. In 2019 she joined the lab of Jesper Olsen at the Novo Nordisk Foundation Center for Protein Research in Copenhagen, where she is working on further applications of mass spectrometry-based proteomics to study signaling and disease.
Emerge Webinar Series Episode 1
Wednesday June 2 at 16:00 CEST
Uncovering the Enzymology and Function of Protein Methylation through Mass Spectrometry based Proteomics
Dr. Magnus Jakobsson, Lund university
In support of emerging researchers, we are introducing the EMERGE webinar series with a specific focus on highlighting novel methods and solutions that labs are implementing to tackle the challenges associated with applying omics technologies in a routine way.
At ReSyn Biosciences we focus on efficiency and reproducibility to develop novel workflows for biological Mass Spectrometry and Bioseparation.
Dr Jakobsson received a PhD in 2013 from Oslo University with his thesis entitled: “Characterization of novel human protein methyltransferases”, and subsequently joined the the laboratory of Dr Jesper V Olsen at the Novo Nordisk Foundation Centre for Protein Research, Copenhagen University.
Since 2019 Magnus has been based at Lund University, where he is a co-leader of the Proteoforms@LU MS platform, focusing on post translational modifications and protein variants. He is also a research group leader at the department of Immunotechnology, where his research focuses on aspects covering both basic and translational research, including the development of proteomics workflows for analysis of “orphan” PTMs, the quantitative analysis of proteins and their regulatory PTMs for developing new cancer diagnostics.
Live Demo of Acusera 24•7 QC Management Software
Tuesday May 25, 1 pm CEST
Following on from our successful webinar, Randox Laboratories are pleased to invite you to an online demo of our Acusera 24•7 QC Management Software.
Throughout the previous webinar, key speaker Margaret Le Roux highlighted the benefits of implementing a quality control software in a laboratory, specifically focusing on the use of sigma metrics, %bias, total error, uncertainty of measurement and other statistical reports.
An automated QC software, such as Acusera 24•7, can help to enhance performance assessment, improve QC strategy and meet regulatory requirements. This demo session aims to provide an insight to our state-of-the-art software package.
Webinar: The Need for Robust Molecular Quality Assurance in the Wake of the Pandemic
Wednesday May 26, 2 pm CEST
This educational webinar will discuss topics surrounding the importance of third party molecular Quality Control and External Quality Assessment, as well as the clinical impacts of good or poor QC management. Furthermore, Randox Molecular Product Specialists will detail our extensive product ranges of Qnostics (Molecular QC) and QCMD (Molecular EQA).
Webinar on the utilisation of Quality Control software and sigma metrics for the identification of performance issues.
Tuesday May 18, 1 pm CEST
Acusera 24•7 is an automated QC software which helps to enhance performance assessment, improve QC strategy and meet regulatory requirements.
The webinar will specificlaly focus on the use of sigma metrics, %bias, total error, uncertainty of measurement and other statistical reports.
Towards Standardizing Flow Cytometry Sample Preparation Workflows without Centrifugation
Wednesday May 13, 5 pm CEST
How much further along would you be if your cell and single nuclei sample prep methods were more consistent, less labor-intensive, and retained more precious material? We’ve teamed up with flowcytometryUK and Charles River Laboratories to discuss how Laminar Wash technology can help standardize, optimize, and improve cell and single nuclei suspension prep as the front-end to generating quality flow cytometry data.
Please join us live on Thursday 13 May for a webinar featuring Noma Ngwenya, Application Scientist at Curiox Biosystems, and Christoph Eberle, Ph.D., Principal Scientist II at Charles River, for an informative webinar, featuring:
- An introduction to Laminar Wash technology in support of flow cytometry
- Improvements in single nuclei retention and antibody consumption at Cerevance, a clinical-stage CNS therapeutics company
- Examples of how Charles River is using Laminar Wash to standardize its flow cytometry sample prep
Date: Wednesday May 13 2021
Time: 5:00 pm CEST
Mission Bio Webinar
How Do You Gain Insight into Disease Evolution?
We’re delighted to be hosting a webinar with FIMM, where they tackle some of the most difficult challenges in genomic research by using information from genome sequences to advance the understanding of biology and improve health.
As a pioneer in high-throughput single-cell multi-omic analysis, Mission Bio has developed a platform to genotype and phenotype from the same cell.
During the webinar we will share:
- General Tapestri Overview including SNV, CNV, and protein capabilities
- Hematology applications
Date: Monday, April 19, 2021
Time: 9:00 AM CET
Reliable Gene Silencing with Exceptional siRNA Specificity by High Complexity siPOOLs
siRNA pools (siPOOLs) are high complexity pools of 30 optimally-designed siRNAs that were demonstrated to efficiently remove off-target effects and improve reliability of results (Hannus et al., 2014).
siPOOLs are suited for use against coding or long non-coding RNAs, selected isoforms or closely-related genes, and can be applied in combination to study synergistic gene interactions (Welsbie et al., 2017).
siPOOLs are ideal tools in drug discovery for target validation and target identification with custom or ready-made siPOOL libraries.
Qnostics Quality Controls for Molecular Diagnostic Assays in Infectious Disease
Wednesday March 24 at 10-11 am (CET)
Importance of Independent Third Party Controls
Test for the dynamic range of a molecular assay using Analytical Q Panels
Test the comparable of Methods vs Robotic systems using Molecular Q Panels
Undertake equipment validations and staff training using Medium Q Controls.
Presented by Dwaine R. Vance BSc (Hons), DIS, PhD.
Mission Bio Technology and Applications
New Single Cell Genomics and Multiomics Service
We´re delighted to be hosting a webinar with SciLifeLab clinical Genomics Facility, where they tackle some of the most difficult challenges in genomic research by using information from genome sequences to advance the understanding of biology and improve health.
Centrifuge-Free Automation of Suspension Cell Sample Preparation
Webinar Wednesday February 24 10 am (EST)
Automating cell wash workflows with a centrifuge is challenging and expensive.
Alternatively, Laminar Wash™ technology offers a gentle, reproducible, and high-throughput alternative to preparing suspension cell samples without subjecting them to damaging gravitational forces.
Join us to find out how Laminar Wash:
Overcomes the challenges of automating sample prep
Offers several integration options to streamline your laboratory workflow
Improves cell suspension sample quality for downstream analysis
Malcolm Crook, PhD, Technical Director, Peak Analysis & Automation
Ann Wang, Field Application Specialist, Curiox Biosystems