Cutting Edge Technologies for

Cell- and Molecular Biosciences in the Nordics

Creating value for our customers, suppliers and staff, and ultimately for the public who benefits from scientific discovery. 

What we operate in

Cell Biology

Faster and Easier Flow Cytometry Sample Prep, Synthetic mRNA for Research and Clinical Labs, Next Generation Cell Recovery for Immuno-Oncology etc.

Diagnostics

Anti-Müllerian Hormone (AMH) Quality Control, RIQAS Anti-SARS-CoV-2 Serology EQA Programme, Molecular Controls for Infectious Disease etc.

Genomics

Tapestri Solution for Tumor Profiling in Single Cell, Ultimate Exonic Coverage, Liquid Biopsy Panels etc.

NGS, PCR, qPCR

Direct PCR of Crude Samples without Template Purification, highQu PCR & qPCR Reagents Performance Excellence etc.

Proteomics

Electrospray ionization emitters, RAS proteins for oncology research, MagReSyn NTA beads etc.

Water purification and filtering

Genie Purist: Dedicated for Ultrapure (Type I) Water, Operational Reliability and Ease-of-Use etc.

News & Highlights

ThinkCyte logo

Label-Free Cell Characterization and Sorting Empowered by AI

Based on the core technology Ghost Cytometry which enables supervised or unsupervised machine learning-based sorting, ThinkCyte offers the platform VisionSort. 

The system provides cellular fingerprints with morphometric readouts in high resolution, on top of standard fluorescence-based sorting.

VisionSort is the perfect addition to conventional cell sorters, by providing unbiased, label-free cell characterization and sorting, supported by an embedded AI algorithm.

Biolegio logotype oligonucleotide synthesis

Custom oligonucleotide synthesis; high quality service, speed and flexibility

Biolegio offers a range of products, spanning from highly modified and specialised oligos, to standard DNA oligo synthesis.

Applications covered are sequencing, NGS, PCR, Realtime-PCR, SNP detection, genotyping, gene expression and mutation detection.

  • Long oligo synthesis
  • Modified and standard oligos
  • Probes for Realtime-PCR
  • Custom RNA synthesis
  • NGS grade oligonucleotides
  • Bulk scale synthesis 7 OEM oligos
  • SARS-CoV-2 primers & probes
 
MissionBio single cell MRD vision image

Mission Bio Announces Launch of Single-Cell Measurable Residual Disease (MRD) Assay Aimed to Advance Personalized Healthcare for Blood Cancer Patients

As the only solution to integrate genotypic and immunophenotypic assessment, the scMRD AML Multiomics Assay targets 40 genes for single-cell DNA sequencing based on current international AML MRD guidelines, such as European LeukemiaNet, and 17-plex antibody-oligonucleotide conjugate (AOC) panel curated for key biomarkers associated with AML MRD. 

Through a seamlessly integrated workflow, the assay allows clinician-researchers to:

  • Distinguish true MRD from pre-leukemic or precursor clones with a limit of detection of 0.01%,
  • Reveal clonal architecture (co-occurrence and zygosity of mutation) and uncover the order of acquisition of mutations (phylogeny),
  • Track clonal dynamics and immunophenotypic drifts through disease course to identify therapeutic targets and therapy-resistance subclones.
Cell suspension sample prep

Enabling Accurate Biological Analysis Through Automation

Laminar Wash technology makes it easy for applications that require a high degree of automation such as screening final product for cell therapeutics. Laminar Wash systems can replace centrifuge integrations and only require one robotic movement instead of over 20 movements. Integration using Laminar Wash technology can:

  • Reduce hands-on time and save FTE resources
  • Lower the CVs of results
  • Easily accomodate on-deck or off-deck automation

Special Offer: Hot Start PCR with Less Side Products, ALLin™ Hot Start Taq Polymerase & Mastermix

Superior sensitivity polymerase generating less side products and low copy detection in complex
templates with size up to 6 kb. Highly specific polymerase thanks to efficient blocking at room
temperature. The ALLin™ Buffer includes dNTPs, Magnesium, enhancers, and stabilizers.

10% 4th Quarter Discount

Celemics WES sequencing

Celemics Whole Exome Sequencing Panel

Celemics Whole Exome Sequencing Panel is the most comprehensive WES panel in the market, covering all target regions of major WES panels in the market.

The panel does not compromise uniformity and performs well against hard-to-capture regions such as GC-rich regions.

Azure chemiSOLO chemiluminescence imager

New Azure chemiSOLO personal chemiluminescent imager

The chemiSOLO detects low-expressing proteins with femtogram sensitivity and captures marker images at the push of a button.

A unique web browser interface allows the chemiSOLO to be controlled by phone, tablet, or PC, without the need to install any additional software.

In addition to Western blots, the chemiSOLO captures pictures of colorimetric blots or visible stained protein gels, like Coomassie blue or silver stain.

The chemiSOLO’s wide dynamic range can be further enhanced by using EDR, our Extended Dynamic Range function. This feature allows for linear, quantitative data, while avoiding saturation.

Celloger Nano Real-Time Cell Monitoring

The super compact and intuitive live cell imaging system, Celloger Nano- got everything you need to perform your sophisticate laboratory works. Equipped with exceptional flourescence and auto focusing technology, precise stage controller, and user-friendly software, accelerates your cell-based research works.

Acusera serum indices quality control

Identiy pre-analytical errors in haemolyzed, icteric and lipemic (HIL) samples

The Randox Acusera Serum Indices control is designed to be used to monitor an IVD instrument’s response in the detection of haemolyzed, icteric and lipemic (HIL) samples. This control can be utilised in laboratory interference testing to assist in improving error detection of pre-analytical errors affecting clinical chemistry testing.

This control provides a full range of clinically relevant testing levels, including a negative (-) and three positives (+, ++ & +++)

Lipid Nanoparticles

Non-viral gene delivery with lipid nanoparticles

OZ Biosciences can support every stage of your mRNA-LNP production, from mRNA
synthesis to LNP formulation development, manufacturing and fill & finish.
For any of RNA, DNA or APIs encapsulation, you can provide us with your molecule of
interest and we will formulate it into LNP´s.

  • Custom LNP design services
  • Most advanced nucleic acid delivery system for gene therapy
  • Custom mRNA synthesis services
Digestif

Two-in-one quality control for tryptic digestion and LC-MS performance

Digestif is a universal protein standard to simultaneously assess the quality of sample workup and the performance of your LC-MS system.

  • Control and optimise digestion efficiency
  • Monitor retention times in LC-MS

 

Events

Immunopeptidomics: Isolation of sHLA Peptides from Plasma

Wednesday Nov 8 2023 5 pm (CET)

Soluble HLA (sHLA) peptides are thought to have great potential as biomarkers for different diseases such as cancer. However, efficient enrichment of sHLA peptides from body fluids like plasma has been a bottleneck, requiring 3-5 ml per patient. Here we present IMBAS-MS, an automated magnetic bead based workflow for the efficient enrichment of HLA protein peptide complexes.

The core of IMBAS-MS is the combination of biotinylated antibodies captured by streptavidin magnetic beads allowing for an automated one pot enrichment from only 200 µl plasma.

In combination with Whisper low-flow gradients, data-independent acquisition (DIA) and computational library-based analysis we acquire deep immunopeptidomes from single measurements, elucidating its origins.

Applied statistics in the Medical Laboratory

Tuesday Oct 31 2023 3 pm (CET)

Our guest speaker for the series will be Stephen MacDonald, CPD assessor and a Principal Clinical Scientist at Cambridge University Hospitals NHS Foundation Trust.

In the first of the three sessions, we will introduce commonly used statistical methods, terms and concepts. Topics will include statistical summaries such as mean, variance, standard deviation and coefficient of variation.

We will draw the distinction between imprecision and bias, and how both contribute to the quality of our results. 

We will learn how statistics are used and what other calculations they feed into, including total error and measurement uncertainty. Using practical examples and case studies to illustrate the concepts discussed we can understand how to apply these statistical principles in your daily laboratory operations.

By the end of this session, participants will:

  1. Gain proficiency in basic statistical measures such as standard deviation and coefficient of variation to quantify and manage analytical variability
  2. Be able to distinguish between systematic and random errors
  3. Acquire the knowledge and skills to calculate total error in laboratory measurements, taking into account both systematic and random error components.
  4. Participants will be introduced to the basics of how statistics are used in understanding Measurement Uncertainty, to combine analytical variability and metrological traceability of laboratory results.

Whether you are a seasoned professional or new to the field, this session will provide valuable insights and practical knowledge that can be immediately applied in your workplace.

About Stephen MacDonald

Stephen MacDonald is a Principal Clinical Scientist in the field of Specialist Hemostasis working at Cambridge University Hospitals NHS Foundation Trust.

Stephen has a keen interest in the statistical assessment of laboratory assay performance and clinical trials. He has focused on determination of uncertainty of measurement in Specialist Hemostasis assays and in developing models to best describe their performance.

This has led Stephen to participating in National Advisory boards for numerous aspects of Laboratory Hemostasis as well as publishing a range of journal articles in The Journal of Laboratory and Precision Medicine and the International Journal of Laboratory Hematology.

Myeloma Matters: Advancing Research and Therapy Development with Single-cell DNA + Protein Multi-Omics

Wednesday Oct 18 2023 5 pm (CEST)

Multiple myeloma is a complex form of plasma cell cancer that is currently untreatable. There are approximately 200,000 new diagnoses each year globally, with a 100% relapse rate and 54% five-year overall survival rate. In spite of significant advancements in treating blood-related cancers, these diseases continue to be a substantial cause of illness and death worldwide.

In this webinar, Dr. Todd Druley, MD, Ph.D., Chief Medical Officer of Mission Bio, and Co-Founder and Chief Technology Officer Dr. Adam Sciambi, Ph.D., will:

• Discuss the clinical impact and horizon of multiple myeloma therapies

• Present a novel approach to multiple myeloma therapeutic development by correlating SNVs, CNVs, and surface epitopes for clonal profiling

• Share clinical data generated by researchers from The Cancer Research Center of Toulouse IUCT-Oncopole and Genentech

Webinar: Pre-Eclampsia and Improving Clinical Pathways with PlGf / sFlt-1

Tuesday Oct 10 2023 3 pm (CEST)

Quantitative determination of placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) in human serum and plasma

This webinar will focus on Pre-Eclampsia and improving clinical pathways with PkGF / sFlt-1, including a brief introduction of Pre-eclampsia and insight into the inclusion of biomarkers sFlt-1 & PlGF.

We will be joined by Professor Tim James, Laboratory Manager and Head BioMedical Scientist in Clinical BioChemistry at Oxford University Hospitals.

Professor James will be discussing his own experiences from Oxford to provide insight, advice and guidance to highlight the clinical significance and favourable outcomes of sFlt-1 & PlGF.

About Professor Tim James:

Professor Tim James is Laboratory Manager and Head Biomedical Scientist in Clinical Biochemistry at Oxford University Hospitals NHS Foundation Trust, a post he has held for over 20 years.
Within this role he manages three laboratory sites including a large teaching hospital service. Working with clinical departments to better understand testing and to ensure optimal utilisation is a key aim of the service. He has worked with many clinical teams to evaluate current testing and where possible introduce new diagnostics where there are clear benefits for patients.
He has published over 120 peer reviewed papers in all areas of clinical chemistry and in the last ten years developed a strong collaboration with the Oxford Obstetric team which has led to a series of publications encompassing diagnosis of pre-eclampsia, developing pregnancy specific reference intervals and identifying newer markers of obstetric disease.

 

Mission statement: Life science, inspired

The importance of customers´ needs

We understand our customers’ needs and know how to operate flexibly in a quickly changing but always demanding market.

10 000 +

Products

Instruments and reagents based on innovation for improved laboratory methods.

1 000 +

Satisfied Customers

Networking with 1000´s of individual scientists in Denmark, Finland, Norway, Sweden, Iceland and Baltic countries.

20 +

Years Of Experience

We know how to operate flexibly in a quickly changing but always demanding market.

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